Speedy™ Human TNFRSF13B/CD267 One-Step ELISA Kit
Sensitivity
1.7 pg/mL
Range
7.8-500 pg/mL
Reactivity
Human
Cat no : SE50178
Synonyms
CD267, TNFRSF13B, CVID, TACI
Validation Data Gallery
Product Information
| Product name | Speedy™ Human TNFRSF13B/CD267 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma |
| Assay type | Sandwich |
| Sensitivity | 1.7 pg/mL |
| Range | 7.8-500 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 23495 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 89% | 73%-102% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 219.9 | 9.6 | 4.3 |
| 2 | 8 | 55.1 | 2.5 | 4.6 |
| 3 | 8 | 28.6 | 0.9 | 3.2 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 222.3 | 10.4 | 4.7 |
| 2 | 16 | 56.0 | 3.2 | 5.8 |
| 3 | 16 | 29.0 | 1.7 | 5.7 |
Background Information
Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B, also known as CD267) is a member of the tumor necrosis factor receptor superfamily. It is a receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS, binding both ligands with similar high affinity. TNFRSF13B plays a crucial role in humoral immunity by mediating activation of transcription factors and is involved in the stimulation of B- and T-cell function. It also promotes T-cell independent antibody responses and plasma cell differentiation, counteracting BAFF-driven B-cell activation. Additionally, the concentration of plasma TNFSF13B may be correlated with immune thrombocytopenia.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | CD267, TNFRSF13B, CVID, TACI |