Speedy™ Human TFF1 One-Step ELISA Kit
Sensitivity
2.3 pg/mL
Range
31.25-2000 pg/mL
Reactivity
Human
Cat no : SE50093
Synonyms
Breast cancer estrogen-inducible protein, HP1.A, pNR 2, PNR-2, Polypeptide P1.A
Validation Data Gallery
Product Information
| Product name | Speedy™ Human TFF1 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma |
| Assay type | Sandwich |
| Sensitivity | 2.3 pg/mL |
| Range | 31.25-2000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 7031 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 81% | 74%-92% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 1,102.0 | 45.5 | 4.1 |
| 2 | 8 | 262.5 | 15.8 | 6.0 |
| 3 | 8 | 124.3 | 5.0 | 4.0 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 1,069.2 | 55.0 | 5.1 |
| 2 | 16 | 257.1 | 16.4 | 6.4 |
| 3 | 16 | 123.2 | 6.8 | 5.5 |
Background Information
Trefoil factor 1 (TFF1) is also named as PNR-2, Polypeptide P1.A (hP1.A), Breast cancer estrogen-inducible protein (BCEI) and Protein pS2. TFF1 is one of three members of the trefoil factor family. While abundant TFF1 expression can be observed in the gastrointestinal epithelium, it is also expressed in other organs, such as the ileum, colon, and pancreas. The known function of TFF1 is to promote the regeneration of gastric mucosa induced by inflammatory injury by encouraging epithelial cell migration, and a similar regenerative effect is also found in the pancreas and liver. Importantly, recent studies have revealed that TFF1 also functions as a tumor suppressor to inhibit gastric, pancreatic, and hepatocellular carcinogenesis, presumably by inhibiting the Wnt/β-catenin pathway. In terms of the esophagus, TFF1 is not expressed in the squamous epithelium of the esophagus but is expressed in the submucosal gland and BE.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | Breast cancer estrogen-inducible protein, HP1.A, pNR 2, PNR-2, Polypeptide P1.A |