Speedy™ Human SALL4 One-Step ELISA Kit
Sensitivity
15.5 pg/mL
Range
39-2500 pg/mL
Reactivity
Human
Cat no : SE50101
Synonyms
DRRS, HSAL4, Sal like protein 4, Sal-like protein 4, Zinc finger protein 797
Validation Data Gallery
Product Information
| Product name | Speedy™ Human SALL4 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma |
| Assay type | Sandwich |
| Sensitivity | 15.5 pg/mL |
| Range | 39-2500 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 57167 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 78% | 72%-84% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 1,303.6 | 26.6 | 2.0 |
| 2 | 8 | 345.3 | 6.5 | 1.9 |
| 3 | 8 | 95.4 | 4.8 | 5.0 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 1,304.1 | 23.1 | 1.8 |
| 2 | 16 | 344.5 | 6.6 | 1.9 |
| 3 | 16 | 95.4 | 5.1 | 5.3 |
Background Information
Spalt-Like Transcription Factor 4 (SALL4) is a zinc-finger transcriptional factor for embryonic stem cell self-renewal and pluripotency. SALL4 overexpression is found in several cancer tissues and hematologic malignancies,suggesting a key role of SALL4 in cancer onset and progression. Reactivation of SALL4 in cancerous cells is a key event in tumorigenesis and confers malignancy features to cells. The SALL4 protein contains several zinc finger cluster (ZFC) domains spread in different parts of the protein which give it both transcription activation and repression functions. SALL4 has two isoforms. SALL4A originates from full length transcript, while SALL4B as a spliced isoform lacks a part of exon 2. SALL4 abundancy is regulated by transcriptional and post-transcriptional mechanisms. Both SALL4A and SALL4B isoforms can bind β-catenin protein and synergistically activate the Wnt/β-catenin signaling pathway.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | DRRS, HSAL4, Sal like protein 4, Sal-like protein 4, Zinc finger protein 797 |