Recombinant Human PRR4 protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg2881
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human PRR4 protein Gln17-Trp134 (Accession# Q16378-1) with a rabbit IgG Fc tag at the C-terminus. |
| GeneID | 11272 |
| Accession | Q16378-1 |
| PredictedSize | 39.5 kDa |
| SDS-PAGE | 40-50 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
PRR4, or proline-rich 4, is a gene in humans that encodes a protein belonging to the proline-rich protein (PRP) family. The PRR4 gene is expressed in various submucosal glands, including the parotid gland, and is considered a potential biomarker for indicating the functional efficiency of these glands. PRR4, also named Nectin 4, serves as adhesion molecule that participate in the organization of epithelial and endothelial junctions and receptor for herpes simplex virus entry.
References:
1. Reymond N, et al. (2001). J Biol Chem. 276(46):43205-15.