Recombinant Human Neurophysin 1 protein (mFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
>90 %, SEC-HPLC
Tag
mFc Tag
Activity
not tested
Cat no : Eg2238
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE >90 %, SEC-HPLC |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human OXT protein Ala32-Arg125 (Accession# P01178) with a mouse IgG Fc tag at the N-terminus. |
| GeneID | 5020 |
| Accession | P01178 |
| PredictedSize | 37.3 kDa |
| SDS-PAGE | 33-48 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Oxytocin (OXT), a nine-amino-acid peptide produced in the hypothalamus and released by the posterior pituitary, is well-known for its actions in parturition, lactation, and social behavior. Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland and acts by binding to oxytocin receptor (OXTR).
References:
1. Erwei Li , et al. (2024) Nature. 625(7993):175-180. 2. Sébastien Dutertre , et al. (2008) J Biol Chem. 283(11):7100-8.