×
Use Able AI chat for product recommendations

Recombinant Human NCR3/NKp30 protein (rFc Tag)(HPLC verified)

Species

Human

Purity

>90 %, SDS-PAGE
>90 %, SEC-HPLC

Tag

rFc Tag

Activity

not tested

Cat no : Eg2635

Validation Data Gallery

  • Purity of Recombinant Human NCR3 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human NCR3 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human NCR3 was greater than 90% as determined by SEC-HPLC.

    The purity of Human NCR3 was greater than 90% as determined by SEC-HPLC.

Product Information

Purity >90 %, SDS-PAGE
>90 %, SEC-HPLC
Endotoxin <0.1 EU/μg protein, LAL method
Activity 
Not tested
Expression HEK293-derived Human NCR3 protein Leu19-Gly135 (Accession# O14931-1) with a rabbit IgG Fc tag at the C-terminus.
GeneID 259197
Accession O14931-1
PredictedSize 38.4 kDa
SDS-PAGE 41-55 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

NCR3 (natural cytotoxicity triggering receptor 3) is part of the natural cytotoxicity receptors (NCRs), which play a crucial role in the immune system, particularly in the function of natural killer (NK) cells. NCR3 is a cell membrane receptor of NK cells that is activated by binding of extracellular ligands, including BAG6 and NCR3LG1. NCR3 is involved in the immune response by facilitating the lysis of tumor cells. It interacts with the T-cell receptor CD3-zeta (CD247).

References:

1. Barrow AD, et al. (2019) Front Immunol. May 7;10:909.
2. Koch J, et al. (2013) Trends Immunol. Apr;34(4):182-91.
3. Hudspeth K, et al. (2013) Front Immunol. Mar 20;4:69.
||
New chat

Able™

正在加载，请稍候...