Recombinant Human NGAL protein (C-10*HIS)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
His Tag
Activity
not tested
Cat no : Eg0268
Validation Data Gallery
Product Information
Purity | >90 %, SDS-PAGE |
Endotoxin | <1.0 EU/μg protein, LAL method |
Activity |
Not tested |
Expression | HEK293-derived Human NGAL protein Gln21-Gly198(Accession# P80188) with a His tag at the C-terminus. |
GeneID | 3934 |
Accession | P80188 |
PredictedSize | 22.3 kDa |
SDS-PAGE | |
Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Neutrophil gelatinase-associated lipocalin (NGAL), also known as lipocalin-2, 24p3, siderocalin, or uterocalin, is a small secreted glycoprotein of 25 kDa. NGAL was initially identified in mature neutrophil granules, but has since been described in many other cell types. NGAL is expressed in renal, endothelial, liver, and smooth muscle cells (SMCs), as well as cardiomyocytes, neurons, and various populations of immune cells, such as macrophages and dendritic cells.
References:
1. Liu, Fenghua et al. Advances in medical sciences vol. 60,1 (2015): 133-8. 2. Buonafine, Mathieu et al. Clinical science (London, England : 1979) vol. 132,9 909-923.