Speedy™ Human MMP3 One-Step ELISA Kit
Sensitivity
10.1 pg/mL
Range
78.1-5000 pg/mL
Reactivity
Human
Cat no : SE50014
Synonyms
EC:3.4.24.17, Matrix metalloproteinase-3, MMP 3, MMP-3, SL-1
Validation Data Gallery
Product Information
| Product name | Speedy™ Human MMP3 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell culture supernatant |
| Assay type | Sandwich |
| Sensitivity | 10.1 pg/mL |
| Range | 78.1-5000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 4314 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 104% | 95%-112% |
| Cell culture supernatant | 103% | 93%-116% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 1,216.5 | 22.2 | 1.8 |
| 2 | 8 | 299.4 | 6.5 | 2.2 |
| 3 | 8 | 157.8 | 4.9 | 3.1 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 1,201.8 | 28.3 | 2.4 |
| 2 | 16 | 302.5 | 14.8 | 4.9 |
| 3 | 16 | 158.5 | 5.0 | 3.1 |
Background Information
Matrix metalloproteinase 3 (MMP-3), also known as Stromelysin-1, localized to chromosome 11q22.3, is a member of the metalloproteinase enzyme family, which consists of approximately 20 zinc-dependent endopeptidases. The main role of MMP3 is involved in the breakdown of the extracellular matrix (ECM) proteins during tissue remodeling in normal physiological processes, such as embryonic development and reproduction. The early studies on MMP-3 focused on its roles in collagen degradation and various pathological conditions, including arthritis, fibrosis, and cancer.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | EC:3.4.24.17, Matrix metalloproteinase-3, MMP 3, MMP-3, SL-1 |