• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Purchase

Recombinant Human CD94/KLRD1 protein (rFc Tag)(HPLC verified)

Species

Human

Purity

>90 %, SDS-PAGE
>90 %, SEC-HPLC

Tag

rFc Tag

Activity

not tested

Cat no : Eg2580

Validation Data Gallery

  • Purity of Recombinant Human CD94 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CD94 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human CD94/KLRD1 was greater than 90% as determined by SEC-HPLC.

    The purity of Human CD94/KLRD1 was greater than 90% as determined by SEC-HPLC.

Product Information

Purity >90 %, SDS-PAGE
>90 %, SEC-HPLC
Endotoxin <0.1 EU/μg protein, LAL method
Activity 
Not tested
Expression HEK293-derived Human CD94 protein Lys32-Ile179 (Accession# Q13241-1) with a rabbit IgG Fc tag at the N-terminus.
GeneID 3824
Accession Q13241-1
PredictedSize 44.4 kDa
SDS-PAGE 50-65 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

CD94, also known as the killer cell lectin-like receptor (KLR) family member, is a type II integral membrane protein related to the C-type lectin superfamily. It is specifically expressed on natural killer (NK) cells and a subset of T cells, and plays a crucial role in stimulating NK cell cytolysis and the release of tumor necrosis factor. CD94 can form heterodimers with different NKG2 proteins (e.g., NKG2A, NKG2C, NKG2E, or NKG2F) to balance the function of NK cells and CD8+ T cells.

References:

1. Jianhua Yu. et al. (2009). J Immunol. 183(8):4968-74.
2. Hong Fang. et al. (2021). Leuk Res. 108:106614.
3. Anasuya Gunturi. et al. (2004). Immunol Res. 30(1):29-34.