Speedy™ Human KIM-1/HAVCR1 One-Step ELISA Kit
Sensitivity
3.1 pg/mL
Range
15.6-1000 pg/mL
Reactivity
Human
Cat no : SE50019
Synonyms
HAVCR1, KIM-1, TIM-1, CD365, HAVcr-1
Validation Data Gallery
Product Information
| Product name | Speedy™ Human KIM-1/HAVCR1 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell culture supernatant, Urine |
| Assay type | Sandwich |
| Sensitivity | 3.1 pg/mL |
| Range | 15.6-1000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 26762 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 85% | 80%-91% |
| Cell culture supernatant | 105% | 97%-110% |
| Urine | 83% | 75%-88% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 527.7 | 8.9 | 1.7 |
| 2 | 8 | 133.4 | 3.6 | 2.7 |
| 3 | 8 | 40.1 | 0.7 | 1.8 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 534.3 | 12.7 | 2.4 |
| 2 | 16 | 132.4 | 3.3 | 2.5 |
| 3 | 16 | 40.0 | 1.2 | 3.1 |
Background Information
Kidney injury molecule 1 (KIM-1, also known as HAVCR1) is a type I membrane glycoprotein that plays a crucial role in various physiological and pathological processes. It is involved in immune responses, viral infections, and renal injury. In the context of renal injury, KIM-1 is highly upregulated in proximal tubule cells and functions as a phosphatidylserine receptor, facilitating the clearance of apoptotic and necrotic cells. Additionally, KIM-1 is involved in immune regulation, including the moderation of asthma and allergic diseases. Soluble forms of KIM-1 can be detected in urine and blood, particularly in patients with renal injury.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | HAVCR1, KIM-1, TIM-1, CD365, HAVcr-1 |