Speedy™ Human IL18BP One-Step ELISA Kit
Sensitivity
0.14 ng/mL
Range
0.47-30 ng/mL
Reactivity
Human
Cat no : SE50045
Synonyms
IL 18BP, IL-18BP, IL18BPa, interleukin 18 binding protein, Interleukin-18-binding protein
Validation Data Gallery
Product Information
| Product name | Speedy™ Human IL18BP One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Urine |
| Assay type | Sandwich |
| Sensitivity | 0.14 ng/mL |
| Range | 0.47-30 ng/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 10068 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 103% | 91%-122% |
| Urine | 123% | 113%-127% |
IntraAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 18.28 | 1.17 | 6.40 |
| 2 | 8 | 4.69 | 0.24 | 5.12 |
| 3 | 8 | 2.41 | 0.13 | 5.39 |
InterAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 18.28 | 1.14 | 6.24 |
| 2 | 16 | 4.61 | 0.25 | 5.42 |
| 3 | 16 | 2.36 | 0.14 | 5.93 |
Background Information
IL-18 Binding Protein (IL18BP) is a soluble protein that acts as a natural antagonist of interleukin-18 (IL-18), a pro-inflammatory cytokine involved in immune responses. It binds to IL-18 with high affinity, preventing IL-18 from interacting with its receptors (IL-18Rα and IL-18Rβ) and thus inhibiting its biological activity. This regulation is crucial for maintaining immune homeostasis and preventing excessive inflammation. IL18BP is a biomarker for disease activity and severity, as well as a therapeutic target in cancer immunotherapy.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | IL 18BP, IL-18BP, IL18BPa, interleukin 18 binding protein, Interleukin-18-binding protein |