Speedy™ Human IL-22 One-Step ELISA Kit
Sensitivity
2.8 pg/mL
Range
7.8-500 pg/mL
Reactivity
Human
Cat no : SE50038
Synonyms
IL22, Cytokine Zcyto18, IL 21, IL 22, IL D110
Validation Data Gallery
Product Information
| Product name | Speedy™ Human IL-22 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell culture supernatant, Urine |
| Assay type | Sandwich |
| Sensitivity | 2.8 pg/mL |
| Range | 7.8-500 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 50616 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 79% | 74%-86% |
| Cell culture supernatant | 100% | 97%-102% |
| Urine | 93% | 88%-98% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 269.7 | 13.5 | 5.0 |
| 2 | 8 | 73.1 | 5.5 | 7.5 |
| 3 | 8 | 33.2 | 1.9 | 5.7 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 279.0 | 22.7 | 8.1 |
| 2 | 16 | 74.1 | 5.5 | 7.4 |
| 3 | 16 | 34.2 | 1.8 | 5.3 |
Background Information
Interleukin 22 (IL-22) is a member of the human type I interferon family, which includes IL-10. IL-22 has the potential to interact with IL-10 because it binds to the IL-10R2c chain with IL-22R1 in its receptor complex. Binding can be blocked by the soluble receptor, IL22 binding protein (IL22BP). Although known as a Th17 cytokine, IL-22 is also expressed by a wide range of immune cells, including NK T, γδ T, and NK cells. IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | IL22, Cytokine Zcyto18, IL 21, IL 22, IL D110 |