Recombinant Human IFNA16 protein (rFc Tag)(HPLC verified)
Species
Human
Purity
>90 %, SDS-PAGE
>90%, SEC-HPLC
Tag
rFc Tag
Activity
not tested
Cat no : Eg5103
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE >90%, SEC-HPLC |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human IFNA16 protein Cys24-Asp189 (Accession# P05015) with a rabbit IgG Fc tag at the N-terminus. |
| GeneID | 3449 |
| Accession | P05015 |
| PredictedSize | 46.5 kDa |
| SDS-PAGE | 48-55 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in 0.5M arg, 30mM Tris, pH8.0. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Interferons (IFN) are a family of cytokines with potent anti-viral, antiproliferative and immunomodulatory properties, classified based on their binding specificity to cell surface receptors. IFNA16 has been shown to be upregulated during chronic HIV infection and might play a role in lipid accumulation and fatty acid deposition in porcine muscle.
References:
1. Pestka S. et al. (1987). Annu. Rev. Biochem. 56:727. 2. Lavender K.J. et al. (2016). J. Virol. 90:6001.