Recombinant Human HP protein (rFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg6628
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human HP protein Val19-Asn406 (Accession# P00738) with a rabbit IgG Fc tag at the N-terminus. |
| GeneID | 3240 |
| Accession | P00738 |
| PredictedSize | 70.2 kDa |
| SDS-PAGE | 47-50 kDa and 77-98 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
HP(Haptoglobin) is also named as zonulin and belongs to the peptidase S1 family. HP, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha(16 kDa and 9 kDa) and 2 beta(40 kDa) polypeptides that are covalently associated by disulfide bonds. Recent studies of haptoglobin show that certain oligosaccharide structures predominate in different diseases.
References:
1. Okuyama, Noriko et al. Int J Cancer. vol. 118,11 (2006): 2803-8. 2. Eckersall, P D, and J G Conner. Comp Biochem Physiol B. vol. 96,2 (1990): 309-14.