Speedy™ Human FGF19 One-Step ELISA Kit
Sensitivity
0.8 pg/mL
Range
7.8-500 pg/mL
Reactivity
Human
Cat no : SE50025
Synonyms
FGF 19, FGF-19, Fibroblast growth factor 19, UNQ334/PRO533
Validation Data Gallery
Product Information
| Product name | Speedy™ Human FGF19 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell culture supernatant |
| Assay type | Sandwich |
| Sensitivity | 0.8 pg/mL |
| Range | 7.8-500 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 9965 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 92% | 91%-93% |
| Cell culture supernatant | 82% | 75%-87% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 248.6 | 3.4 | 1.4 |
| 2 | 8 | 63.3 | 1.6 | 2.5 |
| 3 | 8 | 31.0 | 0.9 | 3.1 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 248.9 | 3.8 | 1.5 |
| 2 | 16 | 63.2 | 1.6 | 2.5 |
| 3 | 16 | 31.3 | 0.9 | 2.9 |
Background Information
Fibroblast growth factor (FGF)19 is a hormone that regulate metabolic processes particularly during feeding or starvation, thus ultimately influencing energy production. FGF19 is secreted by the intestines during feeding and negatively regulates bile acid synthesis and secretion. FGF19 is regarded as late-acting hormones because its functions are only used after insulin and glucagon have completed their actions. FGF19 shows extensively functional overlap in terms of improving glucose tolerance, insulin sensitivity, weight loss, and lipid, and energy metabolism, particularly in pathological conditions such as diabetes, obesity, metabolic syndrome, and cardiovascular and renal diseases. Most patients with these metabolic diseases exhibit reduced serum FGF19 levels, which might contribute to its etiology.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | FGF 19, FGF-19, Fibroblast growth factor 19, UNQ334/PRO533 |