Speedy™ Human E-selectin/CD62E One-Step ELISA Kit
Sensitivity
4.4 pg/mL
Range
15.6-1000 pg/mL
Reactivity
Human
Cat no : SE50060
Synonyms
CD62E, E-selectin, CD62 antigen-like family member E, E selectin, ELAM
Validation Data Gallery
Product Information
| Product name | Speedy™ Human E-selectin/CD62E One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma |
| Assay type | Sandwich |
| Sensitivity | 4.4 pg/mL |
| Range | 15.6-1000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 6401 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 104% | 71%-119% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 515.4 | 11.3 | 2.2 |
| 2 | 8 | 133.5 | 3.5 | 2.6 |
| 3 | 8 | 39.8 | 1.6 | 4.0 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 515.0 | 10.1 | 2.0 |
| 2 | 16 | 133.6 | 3.9 | 2.9 |
| 3 | 16 | 39.7 | 1.8 | 4.5 |
Background Information
E-selectin (Endothelial Leukocyte Adhesion Molecule-1, also known as CD62E) is a critical adhesion molecule expressed on endothelial cells. It plays a crucial role in the initial steps of leukocyte recruitment to sites of inflammation, facilitating the rolling and adhesion of leukocytes to the endothelium. This process is essential for the immune response to infection and injury. E-selectin is upregulated in response to inflammatory cytokines such as IL-1, TNF-α, and bacterial lipopolysaccharide (LPS), and it interacts with various glycan ligands on leukocytes, including PSGL-1, ESL-1, CD44, and CD43.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | CD62E, E-selectin, CD62 antigen-like family member E, E selectin, ELAM |