Recombinant Human CD81 protein (hFc Tag)
Species
Human
Purity
>90 %, SDS-PAGE
Tag
hFc Tag
Activity
not tested
Cat no : Eg1035
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <0.1 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Human CD81 protein Phe113-Lys201 (Accession# P60033) with a human IgG1 Fc tag at the C-terminus. |
| GeneID | 975 |
| Accession | P60033 |
| PredictedSize | 36.5 kDa |
| SDS-PAGE | 34-37 kDa, reducing (R) conditions |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
CD81 (also known as TAPA1or TSPAN28) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Many of these members are expressed on leukocytes and have been implicated in signal transduction, cell-cell interactions, and cellular activation and development. CD81 is involved in signal transduction and cell adhesion in the immune system (PMID: 9597125).
References:
1.Oren R.et al.(1990) Mol Cell Biol.10(8):4007-15. 2.Takahashi S.et al.(1990) J Immunol.145(7):2207-13. 3.Kitadokoro K.et al.(2001) EMBO J.20(1-2):12-8. 4.Hemler ME.et al.(2005) Nat Rev Mol Cell Biol.6(10):801-11. 5.Imai T.et al.(1995)J Immunol.155(3):1229-39.