Speedy™ Human CD33 One-Step ELISA Kit
Sensitivity
11.7 pg/mL
Range
125-8000 pg/mL; 250-16000 pg/mL
Reactivity
Human
Cat no : SE50162
Synonyms
CD33 molecule, gp67, p67, Sialic acid-binding Ig-like lectin 3, SIGLEC 3
Validation Data Gallery
Product Information
| Product name | Speedy™ Human CD33 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell lysate |
| Assay type | Sandwich |
| Sensitivity | 11.7 pg/mL |
| Range | 125-8000 pg/mL; 250-16000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 945 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 120% | 113%-127% |
| Cell lysate | 95% | 91%-98% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 4.86 | 0.18 | 3.70 |
| 2 | 8 | 1.03 | 0.08 | 7.77 |
| 3 | 8 | 0.51 | 0.02 | 3.92 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 4.78 | 0.16 | 3.35 |
| 2 | 16 | 1.03 | 0.09 | 8.74 |
| 3 | 16 | 0.51 | 0.02 | 3.92 |
Background Information
CD33 is a type I transmembrane receptor glycoprotein that functions as an immune inhibitory receptor. It is expressed on myeloid cells, including monocytes, macrophages, and microglia, and plays a role in immune regulation and cell adhesion. CD33 is involved in the suppression of immune responses, particularly in the context of Alzheimer's disease, where it inhibits microglial uptake of amyloid beta. Additionally, CD33 is implicated in the regulation of inflammation and immune cell activation.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | CD33 molecule, gp67, p67, Sialic acid-binding Ig-like lectin 3, SIGLEC 3 |