Speedy™ Human CD141/Thrombomodulin One-Step ELISA Kit
Sensitivity
29.8 pg/mL
Range
125-8000 pg/ml, 250-16000 pg/ml
Reactivity
Human
Cat no : SE50059
Synonyms
THBD, Thrombomodulin, CD141, Fetomodulin, THRM
Validation Data Gallery
Product Information
| Product name | Speedy™ Human CD141/Thrombomodulin One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Urine, Cell Lysate |
| Assay type | Sandwich |
| Sensitivity | 29.8 pg/mL |
| Range | 125-8000 pg/ml, 250-16000 pg/ml |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 7056 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 109% | 101%-131% |
| Urine | 95% | 84%-100% |
| Cell lysate | 96% | 93%-98% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 4,059.3 | 221.3 | 5.5 |
| 2 | 8 | 1,041.6 | 60.1 | 5.8 |
| 3 | 8 | 306.5 | 8.8 | 2.9 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 4,014.1 | 168.0 | 4.2 |
| 2 | 16 | 1,005.6 | 59.2 | 5.9 |
| 3 | 16 | 302.2 | 19.3 | 6.4 |
Background Information
Thrombomodulin (THBD, also known as CD141) is an endothelial-specific type I membrane glycoprotein of 105 kDa that binds thrombin, which plays an important role as a natural anticoagulant. It is expressed mostly on the surface of vascular endothelial cells, where it probably be involved in cell differentiation or inflammation. Soluble forms of CD141 have been found in plasma and urine. It has been reported that plasma CD141 is increased in patients with diabetes mellitus, particularly those with diabetic nephropathy.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | THBD, Thrombomodulin, CD141, Fetomodulin, THRM |