Speedy™ Human BST2 One-Step ELISA Kit
Sensitivity
23.4 pg/mL
Range
78.1-5000 pg/mL
Reactivity
Human
Cat no : SE50090
Synonyms
CD317, Bone marrow stromal antigen 2, BST 2, BST-2, CD 317
Validation Data Gallery
Product Information
| Product name | Speedy™ Human BST2 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell lysate |
| Assay type | Sandwich |
| Sensitivity | 23.4 pg/mL |
| Range | 78.1-5000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 684 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 85% | 74%-102% |
| Cell lysate | 94% | 81%-98% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 2,677.5 | 35.1 | 1.3 |
| 2 | 8 | 683.5 | 6.9 | 1.0 |
| 3 | 8 | 349.2 | 5.4 | 1.5 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 2,648.6 | 49.7 | 1.9 |
| 2 | 16 | 687.7 | 8.6 | 1.3 |
| 3 | 16 | 353.3 | 6.7 | 1.9 |
Background Information
BST2 (Bone Marrow Stromal Cell Antigen 2), also known as Tetherin, CD317, or HM1.24, is a type II transmembrane glycoprotein widely involved in immunomodulation and antiviral defense. It restricts viral release and transmission by binding nascent viral particles to the host cell membrane. In addition, BST2 is highly expressed in a variety of human cancers and is closely associated with tumor cell proliferation, invasion, migration, and immune escape. For example, in laryngeal squamous cell carcinoma, high expression of BST2 correlates with poorer patient prognosis. BST2 is also involved in cell membrane integrity and lipid raft formation, and can activate the epidermal growth factor receptor signaling pathway, thus playing a role in tumorigenesis.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | CD317, Bone marrow stromal antigen 2, BST 2, BST-2, CD 317 |