Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
34183-1-PBS targets HMX3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag41398 Product name: Recombinant human HMX3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 82-169 aa of NM_001105574 Sequence: GFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDS 相同性解析による交差性が予測される生物種 |
| Full Name | H6 family homeobox 3 |
| Calculated molecular weight | 357aa, 38 kDa |
| Observed molecular weight | 38 kDa |
| GenBank accession number | NM_001105574 |
| Gene Symbol | HMX3 |
| Gene ID (NCBI) | 340784 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | A6NHT5 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
H6 family homeobox 3 (HMX3) is also named Homeobox protein H6 family member 3 and NKX-5.1. HMX3 is identified as a protein-coding gene, and diseases associated with HMX3 primarily include upper semicircular canal dehiscence and semicircular canal dehiscence syndrome (PMID: 22779713). In addition, as a transcription factor, HMX3 is involved in the regulation of nerve cell types, which is essential for the development of the inner ear and hypothalamus (PMID: 27151948, PMID: 15363417). HMX3 is lowly expressed in CRC, and HMX3 expression was negatively correlated with poor prognosis of CRC patients (PMID: 36204976).