HLA-DMB Recombinant antibody

HLA-DMB Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

230123A3

Cat no : 82922-1-RR

Synonyms

D6S221E, DMB, HLA DMB, HLA-DMB, MHC class II antigen DMB, RING7



Tested Applications

Positive WB detected inRaji cells, Daudi cells, Ramos cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
Sample-dependent, check data in validation data gallery

Product Information

82922-1-RR targets HLA-DMB in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen HLA-DMB fusion protein Ag16320 相同性解析による交差性が予測される生物種
Full Name major histocompatibility complex, class II, DM beta
Calculated molecular weight 263 aa, 29 kDa
Observed molecular weight31 kDa
GenBank accession numberBC027175
Gene symbol HLA-DMB
Gene ID (NCBI) 3109
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). The class II molecules are composed of two non-covalently associated alpha and beta chains. HLA-DMA and HLA-DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides.

Protocols

Product Specific Protocols
WB protocol for HLA-DMB antibody 82922-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols