Histone deacetylases (HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. At least 4 classes of HDAC were identified. Just like other class II HDACs, HDAC7 shuttles in and out of the nucleus depending on different signals. This gene encoding human HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human HDAC7.