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Host
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Species Reactivity
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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

HAVCR1 Polyclonal antibody

HAVCR1 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

IF, IHC, ELISA

Conjugate

Unconjugated

Cat no : 26420-1-AP

Synonyms

CD365, HAVCR, HAVCR 1, HAVCR1, Kidney injury molecule 1, KIM 1, KIM1, T cell membrane protein 1, TIM, TIM 1, TIM1, TIMD 1, TIMD1

Validation Data Gallery

Applications:
  • WB analysis of Jurkat using 26420-1-AP

    WB analysis of Jurkat using 26420-1-AP

    Jurkat cells were subjected to SDS PAGE followed by western blot with 26420-1-AP (HAVCR1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

  • WB analysis of A549 using 26420-1-AP

    WB analysis of A549 using 26420-1-AP

    A549 cells were subjected to SDS PAGE followed by western blot with 26420-1-AP (HAVCR1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  • IHC staining of human colon cancer using 26420-1-AP

    IHC staining of human colon cancer using 26420-1-AP

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 26420-1-AP (HAVCR1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human colon cancer using 26420-1-AP

    IHC staining of human colon cancer using 26420-1-AP

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 26420-1-AP (HAVCR1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human renal cell carcinoma using 26420-1-AP

    IHC staining of human renal cell carcinoma using 26420-1-AP

    Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma tissue slide using 26420-1-AP (HAVCR1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human renal cell carcinoma using 26420-1-AP

    IHC staining of human renal cell carcinoma using 26420-1-AP

    Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma tissue slide using 26420-1-AP (HAVCR1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 26420-1-AP is HAVCR1 Fusion Protein expressed in E. coli.

Tested Reactivity human
Cited Reactivity mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HAVCR1 fusion protein Ag23888 相同性解析による交差性が予測される生物種
Full Name hepatitis A virus cellular receptor 1
Calculated molecular weight 359 aa, 39 kDa
GenBank accession numberBC013325
Gene symbol HAVCR1
Gene ID (NCBI) 26762
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Hepatitis A virus cellular receptor 1 (HAVCR1, also known as TIM-1, KIM-1 or CD365) is a class I integral membrane glycoprotein, with an ectodomain containing Ig-like domain and a mucin domain. HAVCR1 acts as a membrane receptor for hepatitis A virus (HHAV) (PMID: 9658108; 8861957). HAVCR1 provides a costimulatory signal for T cell activation and inhibits the development of peripheral tolerance (PMID: 16284246; 15793575). HAVCR1 may be involved in the regulation of asthma and allergic diseases (PMID: 14534576). It has been reported that HAVCR1 is shed into urine after acute kidney damage and is a marker of renal tubular injury (PMID: 14600030).

Publications

SpeciesApplicationTitle
mouseIHC,IF

Drug Deliv

Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.

Authors - Jing-Bo Hu
View Article