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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87773-1-PBS targets Gpr44 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | G protein-coupled receptor 44 |
| Observed molecular weight | 35 kDa, 40 kDa |
| GenBank accession number | BC111906 |
| Gene Symbol | Gpr44 |
| Gene ID (NCBI) | 14764 |
| RRID | AB_3745746 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9Z2J6 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
GPR44 (PTGDR2/CRTH2) is a Gi-coupled prostaglandin D₂ receptor expressed on Th2 lymphocytes, eosinophils, and basophils, where it mediates chemotaxis and activation of type 2 immune cells. Through PGD₂-dependent signaling, GPR44 plays a central role in allergic inflammation and eosinophilic immune responses, making it an important therapeutic target in asthma and other Th2-mediated diseases.