Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
21531-1-PBS targets GUCA1C in IHC, Indirect ELISA applications and shows reactivity with human, rat samples.
| Tested Reactivity | human, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag16157 Product name: Recombinant human GUCA1C protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-209 aa of BC103993 Sequence: MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFIDFLEFIAAVNLIVQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKAGLGKVKMK 相同性解析による交差性が予測される生物種 |
| Full Name | guanylate cyclase activator 1C |
| Calculated molecular weight | 209 aa, 24 kDa |
| GenBank accession number | BC103993 |
| Gene Symbol | GUCA1C |
| Gene ID (NCBI) | 9626 |
| RRID | AB_3742042 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95843 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
The guanylate cyclase-activating proteins (GCAPs), Ca2+-binding proteins of the calmodulin gene superfamily, function as regulators of photoreceptor guanylate cyclases (PMID: 15336959). Three different GCAPs (GCAP1, GCAP2, and GCAP3) are identified in vertebrate retina (PMID: 12596930). The cone-specific guanylate cyclase-activating protein 3 (GCAP3) has been shown to regulate the enzymatic activity of membrane-bound guanylate cyclases (GCs) in bovine and teleost fish photoreceptors, to an extent comparable to that of the paralog protein GCAP1 (PMID: 35328663).