Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
Product Information
17517-1-AP targets GSK3 beta-216P in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | glycogen synthase kinase 3 beta |
| Calculated molecular weight | 47 kDa |
| GenBank accession number | NM_002093 |
| Gene Symbol | GSK3B |
| Gene ID (NCBI) | 2932 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P49841 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
GSK3A/B belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and GSK-3 subfamily. It participates in the Wnt signaling pathway. GSK3A/B implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. The antibody can recognize GSK3B with phos-Y(216). It may also recognize GSK3A with phos-Y(279).
Publications
| Species | Application | Title |
|---|---|---|
Chin Med J (Engl) USP25 promotes hepatocellular carcinoma progression by interacting with TRIM21 via the Wnt/β-catenin signaling pathway |