GSDMD Recombinant antibody, PBS Only
GSDMD Recombinant Antibody for WB, FC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human, mouse
Applications
WB, FC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2N24
Cat no : 80918-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
Sample-dependent, check data in validation data gallery |
Product Information
80918-1-PBS targets GSDMD in WB, FC, Indirect ELISA applications and shows reactivity with Human, mouse samples.
Tested Reactivity | Human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | GSDMD fusion protein Ag14757 相同性解析による交差性が予測される生物種 |
Full Name | gasdermin D |
Calculated molecular weight | 484 aa, 53 kDa |
Observed molecular weight | 50-53 kDa |
GenBank accession number | BC008904 |
Gene symbol | GSDMD |
Gene ID (NCBI) | 79792 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.