Validation Data Gallery
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Tested Applications
| Positive WB detected in | mouse brain tissue, fetal human brain tissue, rat brain tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
87758-1-RR targets GPR83 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | G protein-coupled receptor 83 |
| Calculated molecular weight | 423 aa, 48 kDa |
| Observed molecular weight | 52 kDa |
| GenBank accession number | BC067473 |
| Gene Symbol | GPR83 |
| Gene ID (NCBI) | 10888 |
| RRID | AB_3745735 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9NYM4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
GPR83 is a class A GPCR expressed in both hypothalamic neuronal circuits and regulatory T cells, linking it to energy balance, stress responses, and immune regulation. Although its endogenous ligands and signaling mechanisms remain incompletely defined, GPR83 is increasingly recognized as a context-dependent modulator of Treg-associated immune tolerance and neuroendocrine control of metabolism. These features position GPR83 as an emerging target in metabolic and immunoregulatory research.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for GPR83 antibody 87758-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |