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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
87491-1-PBS targets GPR15 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | G protein-coupled receptor 15 |
| Calculated molecular weight | 360 aa, 41 kDa |
| Observed molecular weight | 40 kDa |
| GenBank accession number | BC101779 |
| Gene Symbol | GPR15 |
| Gene ID (NCBI) | 2838 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P49685 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
GPR15 is a Gi-coupled GPCR that directs T cell homing to the colon, playing a central role in mucosal immune surveillance and intestinal homeostasis. Through recognition of GPR15L, GPR15 regulates lymphocyte migration and inflammatory tone within the gut. Dysregulation of this axis contributes to inflammatory bowel disease, autoimmune pathology, and altered tumor immune landscapes, highlighting GPR15 as a key mediator of tissue-specific immune trafficking.