Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
25479-1-PBS targets GIPC3-Specific in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | GIPC PDZ domain containing family, member 3 |
| Calculated molecular weight | 34 kDa |
| Observed molecular weight | 40 kDa |
| GenBank accession number | NM_133261 |
| Gene Symbol | GIPC3 |
| Gene ID (NCBI) | 126326 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8TF64 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Human PDZ domain-containing protein GIPC3 is a member of the GIPC (GAIP-interacting protein C-terminus) gene family, which is characterized by a single, conserved PDZ domain and GIPC homology (GH1 and GH2) domains. Aberrant expression of GIPC3 has been evidenced to correlate to the audiogenic seizures and sensorineural hearing loss in mouse and human (PMID: 36301034, 21326233). GIPC3 is upregulated in multiple cancer types, with a significant positive correlation of its expression with Hh signaling identified in melanoma cell lines (PMID: 34224745). This antibody is highly specific for GIPC3 protein.