GDNF Recombinant antibody
GDNF Recombinant Antibody for FC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
FC, ELISA
Conjugate
Unconjugated
CloneNo.
230358A10
Cat no : 83087-1-RR
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | SH-SY5Y cells, U-251 cells |
Recommended dilution
Application | Dilution |
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Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
Sample-dependent, check data in validation data gallery |
Product Information
83087-1-RR targets GDNF in FC, ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | GDNF fusion protein Ag24068 相同性解析による交差性が予測される生物種 |
Full Name | glial cell derived neurotrophic factor |
Calculated molecular weight | 211 aa, 24 kDa |
Observed molecular weight | 32-40 kDa |
GenBank accession number | BC069369 |
Gene symbol | GDNF |
Gene ID (NCBI) | 2668 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Glial-derived neurotrophic factor (GDNF) is a member of the transforming growth factor (TGF)-α family and exhibits potent neuroprotective activity. GDNF is a potent promoter of neuronal survival in the CNS and peripheral nervous system (PNS). It has a relatively high speciicity for dopaminergic neurons and thus become an efective treatment for Parkinson's diseases (PD), with clinical trials currently in progress. Protein dimers of GDNF have a reported molecular weight of 32-40 kDa(PMID: 17982417, PMID: 23251488, PMID: 11429269).
Protocols
Product Specific Protocols | |
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FC protocol for GDNF antibody 83087-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |