Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
16980-1-AP targets GBA3 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag9936 Product name: Recombinant human GBA3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-162 aa of BC029362 Sequence: MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 相同性解析による交差性が予測される生物種 |
| Full Name | glucosidase, beta, acid 3 (cytosolic) |
| Calculated molecular weight | 18 kDa, 54 kDa |
| GenBank accession number | BC029362 |
| Gene Symbol | GBA3 |
| Gene ID (NCBI) | 57733 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H227 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
GBA3(cytosolic beta-glucosidase) is also named as CBG, CBGL1 and belongs to the glycosyl hydrolase 1 family and Klotho subfamily. It catalyses the hydrolysis of O-linkedβ-glycosidic bonds at the non-reducing end of carbohydrates with retention of anomeric configuration. It is a 53-kDa monomeric protein with a pI of 4.7-4.8, present in the liver, kidney, intestine and spleen of humans(PMID:12667141). It has 2 isoforms produced by alternative splicing.