G3BP1 Recombinant antibody, PBS Only
G3BP1 Recombinant Antibody for IF, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
7F14
Cat no : 80777-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| Sample-dependent, check data in validation data gallery | |
Product Information
80777-1-PBS targets G3BP1 in IF, Indirect ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | G3BP1 fusion protein Ag3728 相同性解析による交差性が予測される生物種 |
| Full Name | GTPase activating protein (SH3 domain) binding protein 1 |
| Calculated molecular weight | 466 aa, 52 kDa |
| GenBank accession number | BC006997 |
| Gene symbol | G3BP1 |
| Gene ID (NCBI) | 10146 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
GAP SH3 Binding Protein 1 (G3BP1), also named as G3BP, is an effector of stress granule (SG) assembly. SG biology plays an important role in the pathophysiology of TDP-43 in ALS and FTLD-U. G3BP1 can be used as a marker of SG. It has been shown to function downstream of Ras and play a role in RNA metabolism, signal transduction, and proliferation. G3BP1 is a ubiquitously expressed protein that localizes to the cytoplasm in proliferating cells and to the nucleus in non-proliferating cells. G3BP1 has recently been implicated in cancer biology.
