Validation Data Gallery
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Tested Applications
| Positive WB detected in | LNCaP cells, NCCIT cells, HeLa Cells, Saos-2 cells, K-562 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
87473-1-RR targets FPR1 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | formyl peptide receptor 1 |
| Calculated molecular weight | 38 kDa |
| Observed molecular weight | 38 kDa |
| GenBank accession number | BC005315 |
| Gene Symbol | FPR1 |
| Gene ID (NCBI) | 2357 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P21462 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
FPR1 is a Gi-coupled innate immune GPCR that detects formylated peptides from bacteria and damaged mitochondria, initiating leukocyte chemotaxis and inflammatory activation. Predominantly expressed in neutrophils and monocytes, FPR1 functions as a frontline danger sensor in host defense. Dysregulated FPR1 signaling contributes to infectious susceptibility, acute inflammatory injury, and tumor-associated immune modulation, underscoring its importance in innate immunity and inflammatory disease.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for FPR1 antibody 87473-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |