Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
26164-1-PBS targets FPR1 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag23105 Product name: Recombinant human FPR1 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 140-203 aa of BC005315 Sequence: SLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGI 相同性解析による交差性が予測される生物種 |
| Full Name | formyl peptide receptor 1 |
| Calculated molecular weight | 38 kDa |
| Observed molecular weight | 45 kDa |
| GenBank accession number | BC005315 |
| Gene Symbol | FPR1 |
| Gene ID (NCBI) | 2357 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P21462 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
FPR1 is a Gi-coupled innate immune GPCR that detects formylated peptides from bacteria and damaged mitochondria, initiating leukocyte chemotaxis and inflammatory activation. Predominantly expressed in neutrophils and monocytes, FPR1 functions as a frontline danger sensor in host defense. Dysregulated FPR1 signaling contributes to infectious susceptibility, acute inflammatory injury, and tumor-associated immune modulation, underscoring its importance in innate immunity and inflammatory disease.