Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
34275-1-PBS targets FOXD2 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag41978 Product name: Recombinant human FOXD2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 11-100 aa of NM_004474.4 Sequence: MSSESSPAALSEADADIDVVGGGSGGGELPARSGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPG 相同性解析による交差性が予測される生物種 |
| Full Name | forkhead box D2 |
| Calculated molecular weight | 49kDa，495aa |
| Observed molecular weight | 51 kDa |
| GenBank accession number | NM_004474.4 |
| Gene Symbol | FOXD2 |
| Gene ID (NCBI) | 2306 |
| RRID | AB_3743182 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | O60548 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
FOXD2, as one descendant of the FOX gene family, has been mentioned in many articles to show a high expression in several cancers. FOXD2 showed a high expression in gastric adenocarcinoma tissues and cells, and silencing FOXD2 could hinder gastric adenocarcinoma cell proliferation. In addition, FOXD2 could facilitate gastric adenocarcinoma cell proliferation by activating the expression of its downstream gene IQGAP3 and increasing intracellular Ca2+ concentration (PMID: 37724892).