Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
31264-1-PBS targets FOLR2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Eg0953 Product name: recombinant human FOLR2 protein Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS Tag: C-6*HIS Domain: 17-228 aa of NM_000803.5 Sequence: TMCSAQDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQVNQSWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFESYFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAAMH 相同性解析による交差性が予測される生物種 |
| Full Name | folate receptor 2 (fetal) |
| Calculated molecular weight | 29KD |
| Observed molecular weight | 33-35 kDa |
| GenBank accession number | NM_000803.5 |
| Gene Symbol | FOLR2 |
| Gene ID (NCBI) | 2350 |
| RRID | AB_3669922 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | P14207 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
FOLR2 (Folate Receptor 2), also known as Folate Receptor beta (FR-beta), is a 38 kDa glycoprotein that is anchored to the cell membrane via glycosyl phosphatidylinositol (GPI) linkage . FOLR2 belongs to the folate receptor (FOLR) family, which also includes FOLR1 (FR-α), FOLR3 (FR-γ), and FOLR4. FOLR2 has been shown to be expressed by malignant cells, including myelogenous leukemia cells, but has also been demonstrated to be mainly expressed by tumor-associated macrophages (TAMs).