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Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of mouse spleen tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of mouse spleen using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of human prostate cancer using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of human prostate cancer using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of human spleen tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of human spleen using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of mouse kidney tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of mouse kidney using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of rat heart tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of rat heart using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded rat heart tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of rat kidney tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of rat kidney using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Immunohistochemistry (IHC) staining of rat spleen tissue using FAM46C Polyclonal antibody (25038-1-AP)

    IHC staining of rat spleen using 25038-1-AP

    Immunohistochemical analysis of paraffin-embedded rat spleen tissue slide using 25038-1-AP (FAM46C antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • Featured Product
  • KD/KO Validated

FAM46C Polyclonal antibody

FAM46C Polyclonal Antibody for IHC, ELISA
Cat No. 25038-1-AP
Publications(4)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Synonyms

EC:2.7.7.19, Non-canonical poly(A) polymerase FAM46C, TENT5C, Terminal nucleotidyltransferase 5C

Formulation:  PBS, Azide, Glycerol
PBS, Azide, Glycerol
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Positive IHC detected inhuman prostate cancer tissue, rat spleen tissue, mouse spleen tissue, mouse kidney tissue, human spleen tissue, rat kidney tissue, rat heart tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

25038-1-AP targets FAM46C in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag19147

Product name: Recombinant human FAM46C protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-67 aa of BC131726

Sequence: MAEESSCTRDCMSFSVLNWDQVSRLHEVLTEVVPIHGRGNFPTLEITLKDIVQTVRSRLEEAGIKVH

相同性解析による交差性が予測される生物種
Full Name family with sequence similarity 46, member C
Calculated molecular weight 391 aa, 45 kDa
GenBank accession numberBC131726
Gene Symbol FAM46C
Gene ID (NCBI) 54855
RRIDAB_2879863
Conjugate Unconjugated
Form
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ5VWP2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
IHC protocol for FAM46C antibody 25038-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Cancer Res

Loss of FAM46C promotes cell survival in myeloma.

Authors - Yuan Xiao Zhu
View Article
humanWB

Cancer Res

TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness.

Authors - Yining Tao
View Article
humanWB

Cell Rep

The C-terminal region of TENT5 proteins drives ER-associated mRNA polyadenylation via FNDC3 interaction.

Authors - Lisa Viviani
View Article
humanWB

Cancer Sci

Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells.

Authors - Jo Kanasugi
  • KO Validated
View Article
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