Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
55080-1-PBS targets Ephrin B3 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | ephrin-B3 |
| Calculated molecular weight | 36 kDa |
| Observed molecular weight | 45-50 kDa |
| GenBank accession number | NM_001406 |
| Gene Symbol | EFNB3 |
| Gene ID (NCBI) | 1949 |
| RRID | AB_3743199 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q15768 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Ephrin-B3 is a transmembrane ligand that binds primarily to EphB receptors to mediate bidirectional cell signaling, crucial for neural development, axon guidance, and synaptic plasticity. Highly expressed in the brain and spinal cord, it acts as a midline repellent to guide axonal pathfinding (PMID: 16951161). Ephrin‑B3 is important in the regulation of cell proliferation, differentiation and migration via cell‑cell contact, and can activate the reelin pathway during brain development. The band of ephrin-B3 was identical to phosphorylated ephrin-B at 50 kDa (PMID: 16951161, 21447033).