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  • KD/KO Validated

ERCC6/CSB Polyclonal antibody

ERCC6/CSB Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IP, IF, ELISA

Conjugate

Unconjugated

Cat no : 24291-1-AP

Synonyms

ARMD5, ATP dependent helicase ERCC6, CKN2, Cockayne syndrome protein CSB, COFS, COFS1, CSB, ERCC6, ERCC6/CSB, RAD26



Tested Applications

Positive WB detected inDU 145 cells, HeLa cells, PC-3 cells
Positive IP detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Sample-dependent, check data in validation data gallery

Product Information

24291-1-AP targets ERCC6/CSB in WB, IP, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ERCC6/CSB fusion protein Ag18009 相同性解析による交差性が予測される生物種
Full Name excision repair cross-complementing rodent repair deficiency, complementation group 6
Calculated molecular weight 1493 aa, 168 kDa
Observed molecular weight 170 kDa
GenBank accession numberBC127104
Gene symbol ERCC6
Gene ID (NCBI) 2074
RRIDAB_2879476
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
WB protocol for ERCC6/CSB antibody 24291-1-APDownload protocol
IP protocol for ERCC6/CSB antibody 24291-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Int J Mol Sci

A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches.

Authors - Rongbin Wei
mouseWB,IF

Front Mol Biosci

Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.

Authors - Peng Zou
  • KD Validated
humanWB

Life Sci Alliance

Elevated glucose increases genomic instability by inhibiting nucleotide excision repair.

Authors - Alexandra K Ciminera