Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
98325-1-PBS targets EPCR/CD201 in FC applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Recombinant protein 相同性解析による交差性が予測される生物種 |
Full Name | protein C receptor, endothelial (EPCR) |
Calculated molecular weight | 238 aa, 27 kDa |
GenBank accession number | BC014451 |
Gene Symbol | PROCR |
Gene ID (NCBI) | 10544 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9UNN8 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
EPCR (endothelial cell protein C receptor), also known as CD201, is a type 1 transmembrane protein that is primarily found on endothelial cells. It exhibits sequence and three-dimensional structural homology with the major histocompatibility class 1/CD1 family of proteins, particularly CD1d. It binds activated protein C and enhances protein C activation by the thrombin-thrombomodulin complex. It plays a role in the protein C pathway controlling blood coagulation.