Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
Product Information
19693-1-AP targets EIF2C4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | eukaryotic translation initiation factor 2C, 4 |
| Calculated molecular weight | 97 kDa |
| GenBank accession number | NM_017629 |
| Gene Symbol | EIF2C4 |
| Gene ID (NCBI) | 192670 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9HCK5 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
EIF2C4, also named as AGO4 and KIAA1567, belongs to the argonaute family and Ago subfamily. It is required for RNA-mediated gene silencing (RNAi). EIF2C4 binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. EIF2C4 lacks endonuclease activity and does not appear to cleave target mRNAs. It is also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).
Publications
| Species | Application | Title |
|---|---|---|
J Biol Chem Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury. |