Destrin Monoclonal antibody
Destrin Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat, pig and More (1)
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
1A12D9
Cat no : 67657-1-Ig
Synonyms
Validation Data Gallery
Applications:
Tested Applications
| Positive WB detected in | A549 cells, HeLa cells, human platelet, pig rectum, rat rectum, pig brain, rat brain, mouse brain |
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:3000-1:20000 |
| Sample-dependent, check data in validation data gallery | |
Published Applications
| WB | See 1 publications below |
Product Information
67657-1-Ig targets Destrin in WB, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.
| Tested Reactivity | Human, mouse, rat, pig |
| Cited Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Destrin fusion protein Ag1402 相同性解析による交差性が予測される生物種 |
| Full Name | destrin (actin depolymerizing factor) |
| Calculated molecular weight | 19 kDa |
| Observed molecular weight | 18-19 kDa |
| GenBank accession number | BC009477 |
| Gene symbol | DSTN |
| Gene ID (NCBI) | 11034 |
| RRID | AB_2918496 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
Destrin (also known as actin depolymerization factor, ADF) is an actin-binding protein contributing to cytoskeletal dynamics by promoting rapid actin filament disassembly. By regulating actin cytoskeletal reorganization it plays an important role in the formation of filopodia, which further promotes tumor cell invasion and metastasis. Destrin has been reported to be overexpressed in primary colon cancer.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Destrin antibody 67657-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Nat Cell Biol Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis |
