Validation Data Gallery
Tested Applications
| Positive WB detected in | mouse spleen tissue, mouse thymus tissue, rat spleen tissue, rat thymus tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
33235-1-AP targets DcTRAILR1/TNFRSF23 in WB, ELISA applications and shows reactivity with mouse, rat samples.
| Tested Reactivity | mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Eg5262 Product name: recombinant mouse DcTRAILR1/TNFRSF23 protein Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 30-155 aa of NM_024290.4 Sequence: MPESYSFNCPDGEYQSNDVCCKTCPSGTFVKAPCKIPHTQGQCEKCHPGTFTGKDNGLHDCELCSTCDKDQNMVADCSATSDRKCECQIGLYYYDPKFPESCRPCTKCPQGIPVLQECNSTANTVC 相同性解析による交差性が予測される生物種 |
| Full Name | tumor necrosis factor receptor superfamily, member 23 |
| Calculated molecular weight | 20 kDa |
| Observed molecular weight | 24 kDa |
| GenBank accession number | NM_024290.4 |
| Gene Symbol | Tnfrsf23 |
| Gene ID (NCBI) | 79201 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q9ER63 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Decoy TRAIL receptor 1 (DcTRAILR1), also known as tumor necrosis factor receptor superfamily member 23 (TNFRSF23), is a GPI-anchored mouse TNF receptor superfamily member that lacks a cytoplasmic death domain. It is a decoy TRAIL receptor that can block TRAIL-induced apoptosis (PMID: 12466268). It has been reported that upregulation of DcTRAILR1 can prolong the lifespan of tumor-associated neutrophils (PMID: 39558859; 38207030).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for DcTRAILR1/TNFRSF23 antibody 33235-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |