Validation Data Gallery
Filter:
Tested Applications
| Positive WB detected in | HEK-293T cells, HeLa cells, NIH/3T3 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| IF | See 1 publications below |
Product Information
17274-1-AP targets DZIP1L in WB, IF, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DZIP1L fusion protein Ag11034 相同性解析による交差性が予測される生物種 |
| Full Name | DAZ interacting protein 1-like |
| Calculated molecular weight | 767 aa, 87 kDa |
| Observed molecular weight | 87 kDa |
| GenBank accession number | BC033308 |
| Gene Symbol | DZIP1L |
| Gene ID (NCBI) | 199221 |
| RRID | AB_3669266 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8IYY4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
DZIP1L, or DAZ interacting zinc finger protein 1-like, is a protein implicated in autosomal recessive polycystic kidney disease (ARPKD). DZIP1L has been shown to localize to centrioles and at the distal end of basal bodies, interacting with septin2, a protein that maintains the periciliary diffusion barrier at the ciliary transition zone (PMID: 28530676).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for DZIP1L antibody 17274-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Adv Sci (Weinh) The ARPKD Protein DZIP1L Regulates Ciliary Protein Entry by Modulating the Architecture and Function of Ciliary Transition Fibers |