- Featured Product
- KD/KO Validated
RIPK5 Polyclonal antibody
RIPK5 Polyclonal Antibody for WB, IF, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat and More (1)
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
Cat no : 20102-1-AP
Synonyms
Validation Data Gallery
Applications:
Tested Applications
| Positive WB detected in | mouse brain tissue, rat liver tissue |
| Positive IF detected in | HepG2 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| Sample-dependent, check data in validation data gallery | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
| IHC | See 1 publications below |
| IF | See 1 publications below |
Product Information
The immunogen of 20102-1-AP is RIPK5 Fusion Protein expressed in E. coli.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, monkey, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | RIPK5 fusion protein Ag13678 相同性解析による交差性が予測される生物種 |
| Full Name | dual serine/threonine and tyrosine protein kinase |
| Calculated molecular weight | 66 kDa, 105 kDa |
| GenBank accession number | BC060870 |
| Gene symbol | DSTYK |
| Gene ID (NCBI) | 25778 |
| RRID | AB_10694146 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Protein-serine/threonine and protein-tyrosine kinases (PSK and PTK) comprise two major classes of protein kinases. They provide a key switch dictating the dynamic nature and graded regulation of signal transduction pathway activities in cellular organization. DSTYK is a members of the RIP serine/threonine kinase family which involved in activation of NF-KB, JNK, and p38, and induction of apoptosis. This antibody is specific to DSTYK.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for RIPK5 antibody 20102-1-AP | Download protocol |
| IF protocol for RIPK5 antibody 20102-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Nat Commun Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway. | ||
Cell Death Dis Loss of DSTYK activates Wnt/β-catenin signaling and glycolysis in lung adenocarcinoma
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