Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
32634-1-PBS targets DSCAML1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag36336 Product name: Recombinant human DSCAML1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1879-2053 aa of NM_020693 Sequence: ADRGKNVAVPIPHRANKSDYCNLPLYAKSEAFFRKADGREPCPVVPPREASIRNLARTYHTQARHLTLDPASKSLGLPHPGAPAAASTATLPQRTLAMPAPPAGTAPPAPGPTPAEPPTAPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTSGVGRSQKQGAGAYSKSYTLV 相同性解析による交差性が予測される生物種 |
| Full Name | Down syndrome cell adhesion molecule like 1 |
| Calculated molecular weight | 224 kDa |
| Observed molecular weight | 224 kDa |
| GenBank accession number | NM_020693 |
| Gene Symbol | DSCAML1 |
| Gene ID (NCBI) | 57453 |
| RRID | AB_3742686 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q8TD84 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Down syndrome cell adhesion molecule-like protein 1 (DSCAML1) is a transmembrane protein with ten immunoglobulin (Ig) and six fibronectin type III domains (PMID: 11453658). It is involved in neuronal cell adhesion and plays a crucial role in the development and function of the nervous system. DSCAML1 has been shown to participate in neuronal tiling, avoidance of neurite fasciculation, and axon guidance (PMID: 18216855; 21029858). Additionally, DSCAML1 is required for the proper placement of GABAergic neurons in the entorhinal cortex (ECx) and suppression of seizure susceptibility in rodents (PMID: 33256836).