Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
23228-1-PBS targets DNAAF2 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| Tested Reactivity | human, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag19741 Product name: Recombinant human C14orf104 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 606-837 aa of BC013322 Sequence: LRFSAQDLVYSFFLQFAPENKLSTTEPVISISSNNAVIELAKSPESHGHWREWYYGVNNDSLELQECSNSDQLQGKEERVNEESHLTEKEYIEHCNTPTTDSDSSIAVKALQIDSFGLVTCFQQESLDVSQMILGKSQQPESKMQSEFIKEKSATCSNEEKDNLNESVITEEKETDGDHLSSLLNKTTVHNIPGFDSIKETNMQDGSVQVIKDHVTNCAFSFQNSLLYDLD 相同性解析による交差性が予測される生物種 |
| Full Name | chromosome 14 open reading frame 104 |
| Calculated molecular weight | 837 aa, 91 kDa |
| Observed molecular weight | 100-110 kDa |
| GenBank accession number | BC013322 |
| Gene Symbol | C14orf104 |
| Gene ID (NCBI) | 55172 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | Q9NVR5 |
| Storage Buffer | PBS only{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
DNAAF2 (Dynein Axonemal Assembly Factor 2) is a cytoplasmic protein involved in the assembly and maturation of outer dynein arms (ODAs) in ciliary and flagellar axonemes. DNAAF2 cooperates with DNAAF1, DNAAF3, and other factors to mediate the transport of dynein precursors from the cytoplasm to the ciliary base, and promotes the proper folding and localization of dynein complexes at the axonemal assembly site. Mutations in the DNAAF2 gene cause primary ciliary dyskinesia (PCD), characterized by chronic respiratory tract infections, situs inversus, and male infertility, due to defective mucociliary clearance resulting from impaired ciliary motility.