Validation Data Gallery
Tested Applications
| Positive WB detected in | HepG2 cells, HuH-7 cells, L02 cells, SMMC-7721 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
Product Information
33988-1-AP targets DMBX1 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag41356 Product name: Recombinant human DMBX1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 150-250 aa of BC156881 Sequence: EGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSLTITPVAPGGGLL 相同性解析による交差性が予測される生物種 |
| Full Name | diencephalon/mesencephalon homeobox 1 |
| Observed molecular weight | 41 kDa |
| GenBank accession number | BC156881 |
| Gene Symbol | DMBX1 |
| Gene ID (NCBI) | 127343 |
| RRID | AB_3743134 |
| Conjugate | Unconjugated |
| Form | |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q8NFW5 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol{{ptg:BufferTemp}}7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
DMBX1 is a homeobox transcription factor with tightly regulated expression in the developing diencephalon and mesencephalon, where it governs neuronal differentiation and regional patterning. Acting through sequence-specific DNA binding, DMBX1 orchestrates developmental gene networks essential for central nervous system formation. Aberrant regulation of DMBX1 is associated with neurodevelopmental abnormalities and neural-derived cancers, underscoring its importance in neural lineage specification.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for DMBX1 antibody 33988-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |